學系成員

1. Shih, Y.C., Ooi, L., Li, H.H., Allen, J.C., Hartono, S., Welton, T., Tan, E.K., Chan, L.L., Serial Dynamic Deep Gray Nuclear DTI Changes in Parkinson’s Disease Over Twelve Years. Frontiers in Aging Neuroscience 2023 May. (SCI, 2022 IF=5.702, accepted)
2. Welton, T., Tan, Y.J., Saffari, S.E., Ng, S.Y.E, Chia, N.S.Y., Yong, A.C.W., Choi, X., Heng, D.L., Shih, Y.C., Hartono, S., Lee, W, Xu, Z. Tay, K.Y., Au, W.L., Tan, E.K., Chan, L.L., Ng, ASL, Tan, L.C.S. Plasma neurofilament light concentration is associated with diffusion-tensor MRI-based measures of neurodegeneration in early Parkinson’s Disease. Journal of Parkinson’s Disease 2022. (SCI, 2022 IF=5.52)
3. Shih, Y.C., Ooi, L., Li, H.H., Allen, J.C., Hartono, S., Welton, T., Tan, E.K., Chan, L.L., Serial Dynamic Deep Gray Nuclear DTI Changes in Parkinson’s Disease Over Twelve Years. Neuroimage Clinical 2022 (SCI, 2022 IF=4.891, under review).
4. Shih, Y.C., Tseng, W.Y.I., Montaser Kouhsari, L. Diffusion Tensor Imaging Advances in Parkinson’s Disease: A Mini Review. Frontiers in Aging Neuroscience 2022 (SCI, 2022 IF=5.702, under revision).
5. Welton, T., Hartono, S., Shih, Y.C., Schwarz, S.T., Xing, Y., Auer, D.P., Harel, N., Chan, L.L. Clinical Utility of Ultra-High-Field MRI in Parkinson’s Disease. Movement Disorder 2022 (SCI, 2022 IF=9.698, under review).
6. Hartono, S., Chen, R., Welton, T., Tan, A.S., Lee, W., Teh, P.Y., Chen, C., Hou, W., Tham, W.P., Lim, P.W., Kumar, P., Shih, Y.C., Lee, K.J., Tan, C.S., Tan, E.K., Chan, L.L. Quantitative Iron-Neuromelanin MRI Parameters Associates with Parkinson’s Disease Severity, and Its Composite Marker Matches Expert Performance. European Radiology 2022 (SCI, 2021 IF=7.034, under review)
7. Shih, Y.C., Lin, F.H., Liou, H.H., & Tseng, W.Y.I. Aberrant intrinsic effective connectivity in the hippocampal-diencephalic-cingulate model associates with seizure frequency in unilateral temporal lobe epilepsy. Brain Connectivity 2021 Aug;11(6):457-470. (SCI, 2021 IF=2.657)
8. Koh, Y.H., †Shih, Y.C,, Lim, S.L., Kiew, Y.S., Lim, E.W., Ng, S.M., Ooi, L.Q.R., Tan, W.Q., Chung, Y.C., Rumpel, H., Tan, E.K., Chan, L.L. Evaluation of trigeminal nerve tractography using two-fold-accelerated simultaneous multi-slice readout-segmented echo planar diffusion tensor imaging. European Radiology Feb;31(2):640-649. (SCI, 2021 IF=7.034)
9. Lee, N.C., Peng, W.H., Tsai, L.K., Lu, Y.H., Wang, H.C., Shih, Y.C., Pung, Z.X., Hu, H.Y., Hwu, W.L., Tseng, W.Y.I., Chien, Y.H. Ultrastructural and diffusion tensor imaging studies reveal axon abnormalities in Pompe disease mice. Scientific Reports 2020 Nov 19;10(1):20239. (SCI, 2020 IF=4.380)
10. Chen, C.L., †Shih, Y.C., Liou, H.H., Hsu, Y.C., Lin, F.H., Tseng, W.Y.I. Premature white matter aging in patients with right mesial temporal lobe epilepsy: A machine learning approach based on diffusion MRI data. Neuroimage Clinical 2019;24:102033 (SCI, 2018 IF=4.350)
11. Tsai, T.H., Su, H.T., Hsu, Y.C., Shih, Y.C., Chen, C.C., Hu, F.R., Tseng, W.Y.I. White matter microstructural alterations in amblyopic adults revealed by diffusion spectrum imaging with systematic tract-based automatic analysis. British Journal of Ophthalmology 2019;103(4):511-516 (SCI, 2019 IF=3.611)
12. Shih, Y.C., Tseng, C.E., Lin, F.H., Liou, H.H., Tseng, W.Y.I. Hippocampal atrophy is associated with altered hippocampus-posterior cingulate cortex connectivity in mesial temporal lobe epilepsy with hippocampal sclerosis. American Journal of Neuroradiology 2017;38(3):626-632 (SCI, 2017 IF= 3.653)
13. Chien, H.Y., Gau, S.S., Hsu, Y.C., Chen, Y.J., Lo, Y.C., Shih, Y.C., Tseng, W.Y.I. Altered cortical thickness and tract integrity of the mirror neuron system and associated social communication in autism spectrum disorder. Autism Research 2015;8(6):694-708 (SCI, 2015 IF=3.048)
14. Chang, Y.L., Chen, T.F., Shih, Y.C., Chiu, M.J., Yan, S.H., Tseng, W.Y.I. Regional cingulum disruption, not gray matter atrophy, detects cognitive changes in amnestic mild cognitive impairment subtypes. Journal of Alzheimer’s Disease 2015;44(1):125-138 (SCI, 2015 IF=3.920)
15.  Lin, Y.C., Shih, Y.C., Tseng, W.Y.I., Chu, Y.H., Wu, M.T., Chen, T.F., Tang, P.F., Chiu, M.J. Cingulum correlates of cognitive functions in patients with mild cognitive impairment and early Alzheimer's disease: a diffusion spectrum imaging study. Brain Topography 2014;27(3):393-402 (SCI, 2014 IF=3.468)

1. Shih, Y.C., Seow, P, Wang, H.L.C., Kuek, A.Z.C., Hartono, S., Yan, S.H., Tan, E.K., Chan, L.L. Axonal abnormalities in deep brain nuclear pathways across multiple neurotransmitter systems in de novo Parkinson’s disease patients. 2023 ISMRM & ISMRT Annual Meeting & Exhibition, Toronto, ON, Canada, June 03-08, 2023.
2. Kuo, M.C., Chuang, Y.F., Yan, S.H., Huang, Y.H., Liu, Y.C., Chou, C.J., Fan, Y.T., Chiu, Y.L., Shih, Y.C. The application of customized diffusion MRI white matter atlas of 124 deep brain nuclear pathways to mild cognitive impairment study. The 46th Annual Meeting of the Japan Neuroscience Society. Sendai, Japan, Aug 01-04, 2023. (Oral presentation)
3. Liu, Y.P., Kao, S.C., Chuang, Y.F., Yan, S.H., Huang, Y.H., Liu, Y.C., Chou, C.J., Shih, Y.C., Chiu, Y.L., Fan, Y.T. Alterations in intrinsic functional connectivity between the medial prefrontal-anterior cingulate cortices mediate the pathological aging effects on cognitive functioning. The 46th Annual Meeting of the Japan Neuroscience Society. Sendai, Japan, Aug 01-04, 2023.
4. Wang, H.L.C., Kuo, M.C., Chuang, Y.F., Yan, S.H., Huang, Y.H., Liu, Y.C., Fan, Y.T., Chiu, Y.L., Shih, Y.C. Logical memory loss correlated with dentorubrothalamic tract in mild cognitive impairment and dementia. 
   
5. Shih, Y.C., Seow, P, Hartono, S., Welton, T., Lee, W., Kuek, A.Z.C., Chong, S.L., Ng, S.Y.E., Chia, N.S.Y., Tan, E.K., Tan, L.C.S., Chan, L.L. Altered intrinsic functional connectivity across nine brain networks in early stages of idiopathic Parkinson''s disease. Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31^st Annual Meeting, London, England, UK, May 07-12, 2022.
6. Seow, P., Shih, Y.C., Hartono, S., Lee, W., Chong, S.L., Chen, C.Y.T, Tan, E.K., Chan, L.L. Diffusion MRI Connectometry with Motor and Cognitive Deficits of Pedunculopontine Nucleus Cholinergic Projections in Parkinson’s Disease. Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31^st Annual Meeting, London, England, UK, May 07-12, 2022.
7. Welton, T., Ong, A.A., Hartono, S., Shih, Y.C., Lee, A.; Tan, E.K.; Chan, L.L. Distinct Patterns of Tremor Network Microstructure for Essential Tremor and Parkinson’s Disease. International Parkinson and Movement Disorder Society: 2022 International Congress, Madrid, Spain, Sep. 15-18, 2022.
8. Seow, P., Shih, Y.C., Hartono, S., Lee, W., Kuek, A.Z.C., Ng, S.Y.E., Chia, N.S.Y., Tan, E.K., Chan, L.L. Resting-State Functional Connectivity of the Central Autonomic Network (CAN) in Parkinson’s Disease. Joint Annual Meeting ISMRM-ESMRMB & ISMRT 31^st Annual Meeting, London, England, UK, May 07-12, 2022.
9. Shih, Y.C., Lin, F.H., Cheng, A.K.Z., Liou, H.H., Tseng, W.Y.I. Seizure frequency in relation to effective connectivity of the hippocampal-diencephalic-cingulate in temporal lobe epilepsy. The 29^th Annual Meeting & Exhibition of ISMRM, Virtual Conference, May 15-20, 2021. (Oral presentation)
10.  Shih, Y.C., Ooi, Q.R.L., Hartono, S., Welton, T., Li, H.H., Allen, J.C., Tan, E.K., Chan, L.L. Twelve-year microstructural changes in the deep gray nuclei in Parkinson’s disease: a serial diffusion tensor imaging study. The 29^th Annual Meeting & Exhibition of ISMRM, Virtual Conference, May 15-20, 2021. (Oral presentation)
11. Shih, Y.C., Maréchal, B., Jerez, R.C., Hartono, S., Li, H.H., Chew, I.H.M., E.K., Tan, Chan, L.L. Automated magnetic resonance Parkinsonism index: test-retest reliability and 10-year changes in aging and Parkinon’s disease. The 29^th Annual Meeting & Exhibition of ISMRM, Virtual Conference, May 15-20, 2021.
12.  Welton, T., Hartono, S., Shih, Y.C., Ng, S.Y.E., Chia, N.S.Y., Chong, S.L., Tan, E.K., Chan, L.L., Tan, L.C.S. Microstructure of grey matter nuclei in early Parkinson’s disease: longitudinal study using diffusion kurtosis imaging. he 29th Annual Meeting & Exhibition of ISMRM, Virtual Conference, May 15-20, 2021.

1.    ‘Using neuromelanin-sensitive and multi-shell diffusion MRI to investigate diagnostic imaging biomarkers in the brainstem nuclei for novel data-driven Parkinson’s disease subtypes’ supported by National Science and Technology Council, Taiwan, R.O.C. (NSTC- 111-2222-E-155 -002, 2022-2023, principal investigator)

2.    ‘Advanced application of the low intensity focused ultrasound in neuromodulation’ supported by National Health Research Institutes, Taiwan, R.O.C. (NHRI-111-H02, 2021-2022, co-investigator)

3.    ‘Advanced application of the low intensity focused ultrasound in neuromodulation—extended study’ supported by National Health Research Institutes, Taiwan, R.O.C. (2022-2023, co-investigator)

Patents

1. The 29th ISMRM Merit Award (Magna Cum Laude Award, First Author) (2021)
2. The 29th ISMRM Merit Award (Summa Cum Laude Award, First Author) (2021)
3. The 28th ISMRM Merit Award (Magna Cum Laude Award, First Author) (2020)
4. The 28th ISMRM Merit Award (Summa Cum Laude Award, First Author) (2020)
5. Award of the 2nd Place in RADSC ACP Academic Day 2019 Oral Presentation (2019)
6. The 27th ISMRM Merit Award (Summa Cum Laude Award, Co-First Author) (2019)
7. MOST Student Stipend: The 24th International Society for Magnetic Resonance in Medicine Annual Meeting (ISMRM) (2016)
8. MOST Student Stipend: The 17th Organization for Human Brain Mapping Annual Meeting (OHBM) (2011)