陳芸 教授兼醫護學院籌備處主任

學歷

台灣大學臨床醫學研究所博士


經歷

現職

元智大學 醫學研究所教授

亞東紀念醫院 兼任教學副院長 / 小兒外科主治醫師


經歷

台大醫院小兒外科主治醫師

亞東紀念醫院小兒外科主任

亞東紀念醫院教研部教學室主任

亞東紀念醫院教學部主任

亞東紀念醫院外科部主任

元智大學化材系教授

元智大學化材系副教授

研究專長

醫學教育

臨床外科學

小兒外科

小腸移植及再生

小兒腫瘤研究


期刊論文

1. You-Sheng Lin, Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng, Kuen-Song Lin (2021, Jul). In vivo imaging of neuroblastomas using GD2-targeting graphene quantum dots. Journal of Pediatric Surgery, 56(7): 1227-1232.


2. Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng (2021, Feb). Regulation of ZMYND8 to Treat Cancer. Molecules, 26(4), 1083.


3. Chen-Shuan Chung, Chien-Chen Tsai, Kuan-Chih Chen, Cheng-Kuan Lin, Tzong-Hsi Lee, Huang-Wen Tsai, Yun Chen (2020, Dec). Surveillance of Rejection After Intestinal Transplantation Using an Image Enhanced Endoscopy "VENCH" Scoring System. Transplantation Proceedings, S0041-1345(20) 32834-7. (SCI, 13/24, TRANSPLANTATION).


4. Yun Chen, Huang-Wen Tsai, Ya-Hui Tsai, Sheng-Hong Tseng (2020, Nov). VS-5584, a PI3K/mTOR dual inhibitor, exerts antitumor effects on neuroblastomas in vitro and in vivo. Journal of Pediatric Surgery, S0022-3468(20)30786-7.


5. Yi-Shiou Tseng, Wen-Bin Wu, Yun Chen, Feili Lo Yang, Ming-Chieh Ma (2020, Oct). Small intestine resection increases oxalate and citrate transporter expression and calcium oxalate crystal formation in rat hyperoxaluric kidneys. Clinical Science, 134(19):2565-2580.


6. Siu Chung Ha, Yun Chen, Chee-Chee Koh (2020, Jul). Modified Antibiotic Regimen for Pediatric Complicated Appendicitis to Reduce Infectious Morbidity in Taiwan. Indian Pediatrics, 57(7):676-677.


7. Taizo Hibi, Yun Chen, Ji-Il Kim, Myung Duk Lee, Toshiharu Matsuura, Takehisa Ueno (2020, Apr). Current status of intestinal transplantation in East Asia. Current Opinion in Organ Transplantation, 25(2):165-168.


8. Hong-Hsing Liu, Yu-Chen Lin, Chen-Shuan Chung, Kevin Liu, Ya-Hui Chang, Chung-Hsiang Yang, Yun Chen, Yen-Hsuan Ni, Pi-Feng Chang (2019, Nov). Integrated Counts of Carbohydrate-Active Protein Domains as Metabolic Readouts to Distinguish Probiotic Biology and Human Fecal Metagenomes. Scientific Reports, 9(1):16836.


9. Ming-Chun Chen, Jian-Han Chen, Yun Chen, Ya-Hui Tsai, Cheng-Hung Lee (2019, Sep). Low and decreased prevalence of congenital abdominal wall defect in Taiwan. Journal of Pediatric Surgery, 54(9):1958-1964.


10. Ndumiso Vukile Mdlovu, Kuen-Song Lin, Yun Chen*, Ruey-Shin Juang, Tzu-Wei Chang, Ncobile Bagezile Mdlovu (2019, Aug). Formulation and characterization of multifunctional polymer modified-iron oxide magnetic nanocarrier for doxorubicin delivery. Journal of the Taiwan Institute of Chemical Engineers.


11. Yun Chen, Ya-Hui Tsai, Bor-Jiun Tseng, Sheng-Hong Tseng (2019, Aug). Influence of Growth Hormone and Glutamine on Intestinal Stem Cells: A Narrative Review. Nutrients, 11(8), 1941.


12. Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng, (2019, Jul). Regulation of BS69 Expression in Cancers. Anticancer Research, 39(7), 3347-3351.


13. Fu-Chen Yang, Po-Yuan Chiu, Yun Chen, Tak W. Mak and Nien-Jung Chen (2019, Jun). TREM-1-dependent M1 macrophage polarization restores intestinal epithelium damaged by DSS-induced colitis by activating IL-22-producing innate lymphoid cells. Journal of Biomedical Science, 26(1):46.


14. Yun Chen, Chuan Li, Ya-Hui Tsai, Sheng-Hong Tseng (2019, Jan). Intestinal Crypt Organoid: Isolation of Intestinal Stem Cells, In Vitro Culture, and Optical Observation. Methods in Molecular Biology, 1576:215-228.


15. Yun Chen, Sheng-Hong Tseng, Chee-Chee-Koh, Chen-Shuan Chung, Chia-Chi Weng, Ya-Hui Tsai (2018, Dec). The Zinc Deficiency and Long-term Outcome in the Cases after Isolated Intestinal Transplantation in Taiwan. Transplantation Proceedings, 50: 2771-2774.


16. Ndumiso Vukile. Mdlovu, Fikile Agath Mavuso, Kuen-Song Lin*, Tzu-Wei Chang, Yun Chen,*, Ya-Hui Tsai, Steven S.-S. Wang, Chun-Ming Wu, Ncobile Bagezile Mdlovu, You-Sheng Lin (2018, Nov). Iron oxide-pluronic F127 polymer nanocomposites as carriers for a doxorubicin drug delivery system. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 562, 361-369.


17. Yun Chen, Xiang-Qin Yang, Bor-Yuan Tseng, Ya-Hui Tsai, Sheng-Hong Tseng, Cheng-Hung Lee, Chao-Ling Yao (2018, Nov). Deferoxamine preconditioning activated hypoxia-inducible factor-1alpha and MyD88-dependent Toll-like receptor 4 signaling in intestinal stem cells. Journal of Pediatric Surgery, 53(11); 2349-2356.


18. Ndumiso Vukile Mdlovu, Yun Chen,*, Kuen-Song Lin*, Ming-Wei Hsu, Steven S.-S. Wang*, Chun-Ming Wu, You-Sheng Lin (2018, Oct). Multifunctional Nanocarrier as a Potential Micro-RNA Delivery Vehicle for Neuroblastoma Treatment. Journal of the Taiwan Institute of Chemical Engineers, 96, 526-537.


19. Chen-Shuan Chung, Chi-Ming Tai, Tien-Yu Huang, Chen-Wang Chang, Kuan-Chih Chen, Chao-Ming Tseng, Horng-Yuan Wang, Cheng-Hsin Chu, Jiann-Ming Wu, Yun Chen, Hsiu-Po Wang (2018, Aug). Small bowel tumors: A digestive endoscopy society of Taiwan (DEST) multicenter enteroscopy-based epidemiologic study. Journal of the Formosan Medical Association, 117(8):705-710.


20. Yun Chen, Shih-Ting Hung, Emily Chou and Ho-Shing Wu (2018, Apr). Review of Polyhydroxyalkanoates Materials and other Biopolymers for Medical Applications. Mini-Reviews in Organic Chemistry , 15(2), 105-121.


21. Yun Chen, Cheng-Hung Lee, Bor-Yuan Tseng, Ya-Hui Tsai, Huang-Wen Tsai, Chao-Ling Yao, Sheng-Hong Tseng (2018, Mar). AZD8055 Exerts Antitumor Effects on Colon Cancer Cells by Inhibiting mTOR and Cell-cycle Progression. Anticancer Research, 38(3),1445-1454. (SCI).


22. Yun Chen, Sheng-Hong Tseng, Chao-Ling Yao, Chuan Li, and Ya-Hui Tsai (2018, Mar). Distinct Effects of Growth Hormone and Glutamine on Activation of Intestinal Stem Cells. Journal of Parenteral and Enteral Nutrition, 42(3), 642-651. (SCI, 15/81, NUTRITION & DIETETICS).


23. Chen-Shuan Chung, Tzong-His Lee, Cheng-Tang Chiu, Yun Chen* (2017, Dec). “Snowmelt Sign” and “Corkscrew Microvessels” Predicting Epithelium Regeneration After Acute Rejection of Small-Bowel Transplantation: A Case Report. Transplantation Proceedings, 49(10), 2419-2421. (SCI).


24. Wei-Lung Tseng, Hsu-Hsien Hsu, Yun Chen, Sheng-Hong Tseng (2017, Oct). Tumor Recurrence in a Glioblastoma Patient after Discontinuation of Prolonged Temozolomide Treatment. Asian Journal of Neurosurgery, 12(4): 727-730.


25. Yun Chen, Ya-Hui Tsai, and Sheng-Hong Tseng (2017, Jan). HDAC Inhibitors and RECK Modulate Endoplasmic Reticulum Stress in Tumor Cells. International Journal of Molecular Sciences, 18: 258-266.


26. Yun Chen, Ya-Hui Tsai, Bor-Jiun Tseng,Hsin-Yen Pan, Sheng-Hong Tseng (2016, Nov). Suppression of miR-19b enhanced the cytotoxic effects of mTOR inhibitors in human neuroblastoma cells. Journal of Pediatric Surgery, 51(11): 1818-1825.


27. Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng (2016, Nov). Regulation of the Expression of Cytoplasmic Polyadenylation Element Binding Proteins for the Treatment of Cancer. Anticancer Research, 36(11): 5673-5680.


28. Cheng-Hung Lee, Yun Chen, Chi-Fu Cheng, Chao-Lin Yao, Jin-Chia Wu, Wen-Yao Yin, Jian-Han Chen (2016, Sep). Incidence of and Risk Factors for Pediatric Metachronous Contralateral Inguinal Hernia: Analysis of a 17-Year Nationwide Database in Taiwan. PLoS One, 11(9): e0163278.


29. Khalilalrahman Dehvari, Yun Chen (equal first), Ya-Hui Tsai, Sheng-Hong Tseng, Kuen-Song Lin (2016, Sep). Superparamagnetic Iron Oxide Nanorod Carriers for Paclitaxel Delivery in the Treatment and Imaging of Colon Cancer in Mice. Journal of Biomedical Nanotechnology, 12(9): 1734-1745.


30. Kuan-Chih Chen, Yun Chen, Tzong-Hsi Lee, Chen-Shuan Chung, (2016, Sep). Peutz-Jeghers syndrome complicated with small bowel intussusception managed by laparoscopy-assisted transoral single-balloon enteroscopy. Digestive and liver disease: official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 48(9):1098.


31. Chen-Shuan Chung, Pi-Feng Chang, Chun-Hsing Liao, Tzong-Hsi Lee, Yun Chen, Yi-Chia Lee, Ming-Shiang Wu, Hsiu-Po Wang, Yen-Hsuan Ni (2016, Apr). Differences of microbiota in small bowel and faeces between irritable bowel syndrome patients and healthy subjects. Scandinavian journal of gastroenterology, 51(4):410-419.


32. Yun Chen, Ya-Hui Tsai, Sheng-Hong Tseng (2016, Mar). Selenite stimulates the proliferation of intestinal stem cells with elevated anti-oxidative activity. Transplantation Proceedings, 48(2):507-511.


33. Cheng-Hung Lee, Sheng-Hong Tseng, Yun Chen (2015, Dec). Ileal perforation and transanal protrusion of the peritoneal tube in a boy with a ventriculoperitoneal shunt and literature review. Formosan Journal of Surgery, 48(6); 209-213.


34. Huang-Wen Tsai, Fu-Chien Hsieh,Chih-Chun Chang, Ming-Jang Su, Fang-Yeh Chu, Kuo-Hsin Chen, Kuo-Shyang Jeng, Yun Chen (2015, Dec). Clinical Practice of Blood Transfusion in Orthotopic Organ Transplantation: A Single Institution Experience. Asian Pacific journal of cancer prevention, 16(17), 8009-8013.


35. W. T. Kuo, T. C. Lee, H. Y. Yang, C. Y. Chen, Y. C. Au, Y. Z. Lu, L. L. Wu, S. C. Wei, Y. H. Ni, B. R. Lin, Y. Chen, Y. H. Tsai, J. T. Kung, F. Sheu, L. W. Lin & L. C. Yu (2015, Oct). LPS receptor subunits have antagonistic roles in epithelial apoptosis and colonic carcinogenesis. Cell death and differentiation, 22(10), 1590-1604.


36. Kuan-Ai Seon, Sheng-Hong Tseng, Chia-Chee Weng, Yun Chen (2015, May). Colonic perforation after nonsteroidal anti-inflammatory drug use in a 2.7-year-old boy. Journal of pediatric gastroenterology and nutrition, 60(5), e41-43.


37. Chia-Chee Weng, Yun Chen (2015, Mar). Effects of different parenteral nutrition infusions in a patient with short bowel syndrome. Asia Pacific Journal of clinical nutrition, 24(1), 184-187.


38. Mahmoud Shaaban Mohamed, Yun Chen and Chao-Ling Yao (2015, Feb). Intestinal stem cells and stem cell-based therapy for intestinal diseases. . Cytotechnology, 67:177–189.


39. Yun Chen, Man-Ju Ting, Hui-Ling Lin (2015, Feb). Early Inhaled Nitric Oxide in a Child with ARDS after Intestinal Transplantation. Journal of Respiratory Therapy, 14(1): 21-29.


40. Mahmoud Shaaban Mohamed, Yun Chen (equal contribution), Chao-Ling Yao (2014, Jun). A serum-free medium developed for in vitro expansion of murine intestinal stem cells. Biotechnology Journal, 9: 962–970. 本人為第一作者.


41. Yun Chen, Ya-hui Tsai, I-Ning Chou, Sheng-Hong Tseng, Ho-Shing Wu (2014, Jun). Application of biodegradable polyhydroxyalkanoates as surgical Films for ventral hernia repair in mice. International Journal of Polymer Science, Vol. 2014, Article ID 789681, 11 pages, 2014. doi:10.1155/2014/789681.


42. Chun-Jen Liao, Wen-Hsi Wang, Huang-Chien Liang, Yi-Chun Su, Pei-Chi Hsu, Yu-Ming Wang, Yi-Hsin Tsai, Yun Chen, Sheng-Hong Tseng (2014, May). A Novel Foamy Collagen as a Dural Substitute. Biomedical Engineering: Applications, Basis and Communications, Vol. 26, No. 6 (2014) 1450066 (9 pages).


43. Yun Chen and Sheng-Hong Tseng (2014, Apr). Targeting Tropomyosin-receptor Kinase Fused Gene in Cancer. Anticancer Research, 34:1595-1600.


44. Hsin-Yen Pan, Sheng-Hong Tseng, Chia-Chi Weng, Yun Chen (2014). Cellular neurothekeoma of the upper lip in an infant. Pediatrics and neonatology, 55(1), 71-4.


45. Shu-Chen Wei, Yan-Yin Tan, Meng-Tzu Weng, Liang-Chuan Lai, Jen-Hao Hsiao, Eric Y Chuang, Chia-Tung Shun, Deng-Cheng Wu, Ai-Wen Kao, Chiao-Shung Chuang, Yen-Hsuan Ni, Ming-Jium Shieh, Chien-Chih Tung, Yun Chen, Cheng-Yi Wang, Ramnik J Xavier, Daniel K Podolsky, Jau-Min Wong (2014). SLCO3A1, A novel Crohn's disease-associated gene, regulates nf-kappaB activity and associates with intestinal perforation. PloS one, 9(6), e100515.


46. Yun Chen, Shih-Hua Lee, Ya-Hui Tsai, Sheng-Hong Tseng (2014). Ischemic preconditioning increased the intestinal stem cell activities in the intestinal crypts in mice. The Journal of surgical research, 187(1), 85-93.


47. Yun Chen, Ya-Hui Tsai,and Sheng-Hong Tseng (2013, Dec). RECK regulated endoplasmic reticulum stress response and enhanced cisplatin-induced cell death in neuroblastoma cells. Surgery. (Accepted). (SCI, 17/198, SURGERY).


48. Yun Chen, I-Ning Chou, Ya-Hui Tsai and Ho-Shing Wu (2013, Jun). Thermal degradation of Poly(3-hydroxybutyrate), and Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) in Drying Treatment. Journal of Applied Polymer Science, 130: 3659–3667, 2013


49. Yun Chen, Ya-Hui Tsai, and Sheng-Hong Tseng (2013, Jan). Inhibition of cyclin-dependent kinase 1-induced cell death in neuroblastoma cells through the microRNA-34a-MYCN- survivin pathway. Surgery, 153:4-16.


50. C. N. Hsu, S. H. Tseng, S.W. Chang, Y. Chen, (2013). Strongyloides stercoralis infection in an intestinal transplant recipient. Transplant infectious disease: an official journal of the Transplantation Society, 15(4), E139-43.


51. Chen-Ming Huang, Sheng-Hong Tseng, Chia-Chee Weng, Yun Chen (2013). Isolated intestinal transplantation for megacystis microcolon intestinal hypoperistalsis syndrome: case report. Pediatric transplantation, 17(1), E4-8.


52. Man-Ju Ting, Yun Chen, Shi-Chuan Chang (2013). Factors affecting the duration of mechanical ventilation in patients after intestinal transplantation: preliminary results. Acta anaesthesiologica Taiwanica: official journal of the Taiwan Society of Anesthesiologists, 51(3), 108-11.


53. Yun Chen, Ya-Hui Tsai, Yuan-An Liu, Shih-Hua Lee, Sheng-Hong Tseng, Shiue-Cheng Tang (2013). Application of three-dimensional imaging to the intestinal crypt organoids and biopsied intestinal tissues. The Scientific World Journal, 14(2013), 624342.


54. Chee-Chee Koh, Sheng-Hong Tseng, Chia-Chi Weng, Yun Chen* (2012, Dec). Congenital Membrane Caused Duodenal Obstruction and Malpositioning of the Descending Colon: Case Report. Pediatric and Neonatology, 54(4):275-7. (SCI, 96/115, Pediatrics).


55. Hsin-Yen Pan, Sheng-Hong Tseng, Chia-Chi Weng, Yun Chen* (2012, Dec). Cellular Neurothekeoma of the Upper Lip in an Infant: Case Report. Pediatric and Neonatology.


56. Chen-Ming Huang, Sheng-Hong Tseng, Chia-Chee Weng, Yun Chen* (2012, Nov). Isolated intestinal transplantation for megacystis microcolon intestinal hypoperistalsis syndrome: A case report. Pediatric Transplantation, 2012 Nov 20. DOI: 10.1111/petr.12019.


57. Yun Chen, Ya-Hui Tsai, Yu Fang, and Sheng-Hong Tseng (2012, Oct). Micro-RNA-21 regulates the sensitivity to cisplatin in human neuroblastoma cells. Journal of Pediatric Surgery, 47:1797-805.


58. Yun Chen, Ya-Hui Tsai, and Sheng-Hong Tseng. (2012, Aug). Valproic acid affected the survival and invasiveness of human glioma cells through diverse mechanisms. Journal of Neuro-oncology, 109:23-33.


59. Yun Chen, Sheng-Hong Tseng (2012, Jul). The Potential of RECK Inducers as Antitumor Agents for Glioma. Anticancer Res, 32(7): 2991-2998.


60. U-Chon Chio, Sheng-Hong Tseng, Yun Chen* (2012, Jun). Acute appendicitis associated with scarlet fever. Pediatric Infectious Disease Journal, 31(6): 662-663.


61. Jiun-Siang Tan, Sheng-Hong Tseng, Tzung-Hsien Lai, Chia-Chi Weng, Chunyu Kao, Yun Chen* (2012, Jan). Scrotal cystic mass as late presentation of neonatal testicular torsion: report of a case. Journal of Formosan Surgery, 45(1): 29-32.


62. Jia-Rong Yeh, Tzu-Yu Lin, Yun Chen, Wei-Zen Sun, Maysam F. Abbod, Jiann-Shing Shieh (2012). Investigating Properties of the Cardiovascular SystemUsing Innovative Analysis Algorithms Based on Ensemble Empirical Mode Decomposition. Computational and Mathematical Methods in Medicin, 2012:943431. (EI).


63. Shih-Han Chen, Yun Chen, Wen-Kuei Fang, Da-Wei Huang, Kuo-Chang Huang, Sheng-Hong Tseng (2011, Dec). Comparison of craniotomy and decompressive craniectomy in severely head-injured patients with acute subdural hematoma. Journal of Trauma, 71(6):1632-6. (SCI, 44/199, Surgery).


64. Ting-Chun Yeh, Sheng-Hong Tseng, Chia-Chi Weng, Yun Chen* (2011, Nov). Congenital ectopic fistula of a minor salivary gland. Journal of Pediatric Surgery, 46(11):2187-9.. (SCI, 92/199, Surgery).


65. Yuan- An Liu, Yun Chen, An-Shi Chiang, SJ Peng, PJ Pasricha, SC Tang (2011, Oct). Optical clearing improves the imaging depth and signal-to-noise ratio for digital analysis and three-dimensional projection of the human enteric nervous system. Neurogastroenterology and Motility, 23(10):e446-57.


66. Yun Chen, Ya-Hui Tsai, and Sheng-Hong Tseng (2011, Sep). The potential of tetrandrine as a protective agent for ischemic stroke. Molecules, 16:8020-32. (SCI, 26/56, Chemistry, organic).


67. Yun Chen, Ya-Hui Tsai, and Sheng-Hong Tseng (2011, Jul). Combined valproic acid and celecoxib treatment induced synergistic cytotoxicity and apoptosis in neuroblastoma cells.. Anticancer Research, 31:2231-9.


68. Chenyu Kao, Sheng-Hong Tseng, Yun Chen* (2011, May). Laparoscopic reduction of intussusception in children by a single surgeon in comparison with open surgery. Minimally Invasive Therapy, 20:141-145.


69. Yun Chen, Hong-Shiee Lai, Bor-Luen Chiang, Sheng-Hong Tseng*, Wei-Jao Chen (2010, Sep). Tetrandrine Attenuates Dendritic Cell-mediated Alloimmune Responses and Prolongs Graft Survival in Mice. Planta Medica, 76, 1424–1430. (SCI, 56/190, Plant Sciences). NSC 94-2314-B-418-004.


70. Yun Chen, Sheng-Hong Tseng (2010, Sep). The potential of Tetrandrine against gliomas. Anticancer Agents in Medicinal Chemistry, 10(7): 534-42.


71. Jiann-Ming Wu, Yun Chen*, Jin-Cherng Chen, Tzu-Yu Lin, Sheng-Hong Tseng * (2010, Jan). Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. Cancer Letter, 287,187–195.


72. Yun Chen, Jiang G, Yang HR, Gu X, Wang L, Hsieh CC, Chou HS, Fung JJ, Qian S, Lu L* (2009, Sep). Distinct response of liver myeloid dendritic cells to endotoxin is mediated by IL-27. Journal of Hepatology, 51期, p510-519.


73. Yun Chen, Jiann-Ming Wu, Tzu-Yu Lin, Chia-Chan Wu, Kuan-Ming Chiu, Bee-Feng Chang, Sheng-Hong Tseng*, Shu-Hsun Chu (2009, Sep). Tetrandrine ameliorated reperfusion injury of small bowel transplantation. Journal of Pediatric Surgery, 44, 2145–2152.


74. Yun Chen, Jin-Cherng Chen, Sheng-Hong Tseng (2009, Aug). Effect of tetrandrine plus radiation on the neuroblastoma cells. Anticancer Research, 29(8):3163-3172.


75. Yun Chen, Sheng-Hong Tseng (2009, Mar). Mini-laparoscopic gastropexy in a preterm 10-day-old baby with acute gastric volvulus. Journal of Emergency Critical Care Medicine.


76. Tzu-Yu Lin, Sheng-Hong Tseng, Shao-Jung Li, Jin-Cherng Chen, Jiann-Shing Shieh, Yun Chen* (2009, Feb). Tetrandrine increased the survival rate of mice with lipopolysaccharide-induced endotoxemia. Journal of trauma, 66;411-7.


77. Yun Chen, Jin-Cherng Chen and Sheng-Hong Tseng* (2009, Feb). Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats. International Journal of Cancer, 124, 2260–2269.


78. Jin-Cherng Chen, Yun Chen, Jiann-Ming Wu, Yen-Hao Su, Kuo-Feng Tai, Sheng-Hong, Tseng (2006, Aug). Effects of irradiated tumor vaccine and infusion of granulocyte-macrophage colony-stimulating factorand interleukin-12 on established gliomas in rats. Cancer Immunology Immunotherapy, p873-883.


79. Shiu-Dong Chung, Hsu-Dong Sun, Shun-Fa Hung, Bin Chiu, Yun Chen, Jiann-Ming Wu (2008-11): Renal stone-associated squamous cell carcinoma and pyelo-coloduodunal fistula. Urology 72(5): 1013. (SCI)


80. Yun Chen, Sheng-Hong Tseng: Pro- and Anti-angiogenesis Effects of Resveratrol. In Vivo 21:365-370, 2007. (SCI)


81. Jin-Cherng Chen, Yun Chen, Yen-Hao Su, *Sheng-Hong Tseng (2007-7/8): Celecoxib increased expression of 14-3-3 and induced apoptosis of glioma cells. Anticancer Res 27 (4B): 2547-2554. (SCI)


82. Pi-Feng Chang, Yu-Cheng Lin, Yun Chen *, Shu-Jen Yeh (2007-10): Laparoscopic-assisted colonoscopic polypectomy for juvenile polyp in children. A new minimal-invasive therapeutic approach. Surg Laparosc Endosc Percutan Tech. 17(5): 442-443. (SCI)


83. Pei-Chun Lin, Yun Chen *, Shu-Hsun Chu (2007): A survey of trainees’ needs and requirements during ambulatory care education. J Med Education 11:139-49.


84. Tin-Chou Li, Yun Chen, Swei-Ming Lin, *Sheng-Hong Tseng (2007-8): Acute Posterior Fossa Isodense Epidural Hemato ma: Diagnostic Pitfalls on Computed Tomography. J Trauma 63(2):417-9. (SCI)Donald C. Liu, Tony Lin, Mindy B Statter, Lorentto Glynn, Marcovalerio Melis, Yun Chen, Jianghua Zhan, Beth T Zimmermann, William A Loe, Charles B Hill (2006-1): Laparoscopic Nissen fundoplication without division of short gastric vessels in children. J Pediatr Surg 41: 120-25, 2006. (SCI)


85. Shih-Han Chen, Yun Chen, Sheng-Hong Tseng (2006-2): Anaphylactoid reaction after intravenous administration of methylprednisolone sodium succinate in a patient with spinal cord injury - case report Tzu Chi Med J 2006; 18:35-8.


86. Jin-Cherng Chen, Yun Chen, Swei-Ming Lin, Hung-Jen Yang, Chain-Fa Su, *Sheng-Hong Tseng (2006-2): Acute spinal epidural hematoma after acupuncture: case report. J Trauma 60:414-16, 2006. (SCI)


87. Jin-Cherng Chen, Yun Chen, Jyh-Herng Lin, Jiann-Ming Wu, Sheng-Hong Tseng (2006-3,4). Resveratrol suppresses angiogenesis in gliomas: evaluation by color Doppler ultrasound. Anticancer Research Mar-Apr;26(2A):1237-45, 2006. (SCI)


88. Yun Chen, Lin TY, Chen JC, Yang HZ, Tseng SH (2006-5,6): GL331, a topoisomerase II inhibitor, induces radiosensitization of human glioma cells. Anticancer Res. 2006 May-Jun;26(3A):2149-56. (SCI)


89. Lin CY, Yun Chen, Tseng SH (2007-01): Chronic encapsulated intracerebral heematoma. J Clin Neurosci. 14: 58-61. (SCI)


90. Yen-Hao Su, Yun Chen Yun Chen, Sheng-Hong Tseng (2006-12): Pituitary abscess. J of Clin Neuroscience 13: 1038-41.


91. Ming-Yiing Ho, Sheng-Hong Tseng, Chien-Chen Tsai, Yun Chen * (2005-2). Cellular Neurothekeoma with Atypical Features in a Child. Tzu Chi Med J 17:43-45.


92. Sheng-Hong Tseng, Yun Chen, Chun-Jung Chang, Kuo-Feng Tai, Swei-Ming Lin, and Lih-Hwa Hwang (2005-2): Induction of T Cell Apoptosis in Rats by Genetically Engineered Glioma Cells Expressing Granulocyte-Macrophage Colony-Stimulating Factor and B7.1. Clin Cancer Res 11:1639-1649.


93. Jin-Cherng Chen, Sheng-Hong Tseng, Yun Chen, Jeh-En Tzeng, Swei-Ming Lin (2005-4): Cervical dumbbell meningioma and thoracic dumbbell schwannoma in a patient with neurofibromatosis: case report. Clin Neurol Neurosurg 107:253-257.


94. Hong-Shiee Lai, Yun Chen, Wen-Hsi Lin, Chiung-Nien Chen, Hsiu-Chuan Wu, Chee-Jen Chang, Po-Huang Lee, King-Jen Chang, Wei-Jao Chen (2005-5). Quantitative gene expression analysis by cDNA microarray during liver regeneration after partial hepatectomy in rats. Surg Today. 35(5):396-403


95. Tin-Chou Li, Yun Chen, Swei-Ming Lin, Sheng-Hong Tseng (2005-8): Chondroma of the Falx: case report. Tzu Chi Med J 17: 269-272, 2005.


96. Jin-Cherng Chen, Yun Chen, Jiann-Ming Wu, Yen-Hao Su, Kuo-Feng Tai, Sheng-Hong, Tseng (2005-8): Effects of irradiated tumor vaccine and infusion of granulocyte-macrophage colony-stimulating factor and interleukin-12 on established gliomas in rats. Cancer Immunol Immunother Aug 27:1-11 


97. George Mazariegos, Yun Chen, Robert Squires (2005-9): Biological and artificial liver support system in children: A new perspective. Pediatr Crit Care Med. 2005 Sep;6(5):616-617.


98. Yen-Hao Su, Yun Chen, Swei-Ming Lin, *Sheng-Hong Tseng (2005-10): Lung Cancer Metastasis to the Filum Terminale: case report. Tzu Chi Med J 2005; 17:421-23.


99. Yun Chen, Yen-Hao Su, Chih-Hisen Wang, Jiann-Ming Wu, Jin-Cherng Chen and Sheng-Hong Tseng (2005-12): Induction of apoptosis and cell cycle arrest in glioma by GL331 (a Topoisomerase II inhibitor). Anticancer Research 25:4203-4208. (SCI)


100. Tzu-Yu Lin, Yun Chen, Kuan-Ming Chiu, Cheng-Wei Lu, Wei-Horng Jean, Feng-Ming Horng, Shu-Hsun Chu (2005-12). Cell saver does not increase proinflammatory cytokine levels and expression of adhesive molecules in the salvaged blood of patients undergoing off-pump coronary artery bypass surgery. Acta Anaesthesiol Taiwanica 43:211-15, 2005.


101. Jin-Cherng Chen, Yun Chen, Swei-Ming Lin, Sheng-Hong Tseng (2005-12): Sylvian fissure dermoid cyst with intratumoral hemorrhage: case report. Clin Neurol Neurosurg 108:63-66, 2005. (SCI) Sheng-Hong Tseng, Swei-Ming Lin, Jin-Cherng Chen, Yen-Hao Su, Hsin-Yi Huang, Chia-Kang Chen, Po-Yin Lin, Yun Chen* (2004-3): Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats. Clin Cancer Res 10;6:2190-2202.


102. Yun Chen, Yen-Hsuan Ni, and Hong-Shiee Lai (2004-4): Gastrocolocutaneous fistula in a case with congenital short bowel syndrome: a rare complication of percutaneous endoscopic gastrostomy. J Formosan Med Assoc 103(4):306-10.


103. Ho CM. Chen Y. Lai HS. Lin WH. Hsu WM. Chen WJ (2004-5). Comparison of critical conservative treatment versus emergency operation in children with ruptured appendicitis with tumor formation. J Formosan Med Assoc103(5):359-63.


104. Sheng-Hong Tseng, Chih-Hsien Wang, Swei-Ming Lin, Chia-Kang Chen, Hsin-Yi Huang, Yun Chen* (2004-5): Activation of c-Jun-N-Terminal kinase 1 and caspase 3 in the tamoxifen-induced apoptosis of rat glioma cells. J Cancer Res Clin Oncol 130:285-293


105. Yun Chen, Wen-Tsung Hung, Swei-Ming Lin, Hsiao-Lun Li, Chia-Kang Chen, Sheng-Hong Tseng (2004-7): Fetal bovine serum suppressed the apoptosis in the small intestine after total ischemia and reperfusion in mice. J Pediatr Surg 39;7:1077-83


106. Hung-Zen Yang, Sheng-Hong Tseng, Yun Chen, Swei-Ming Lin, *Jin-Cherng Chen (2004-7): Calcified Chronic Subdural Hematoma: case report. Tzu Chi Med J 16:261-265.


107. Yun Chen, Sheng-Hong Tseng, Hong-Shiee Lai, Wei-Jao Chen (2004-7): Resveratrol-induced cellular apoptosis and cell cycle arrest in neuroblastoma cells and antitumor effects on neuroblastoma in mice. Surgery 136;1:57-66.


108. Chih-Hsien Wang, Jyh-Herng Lin, Wen-Hsi Lin, Sheng-Hong Tseng, Yun Chen*, Po-Huang Lee (2004-7/8): Abdominal Wall Endometrioma after Cesarean Section: Case Report. J Formosan Surgery 37:171-174.


109. Yang CY, Lin MT, Wu MH, Wang JK, Chen Y, Shinn-Forng Peng S, Ni YH (2004-8). Acute gastric volvulus in a child with asplenia syndrome. Pediatr Int. 46(4):471-3 (SCI).


110. Juine-Yih Ma, Yu-Cheng Lin, Sheng-Hong Tseng, Tsung-Hsein Lai, *Yun Chen (2004-11): Intra-retroperitoneal duplication cyst. J Formos Med Assoc 103:869-871. (SCI)


111. Yu-Cheng Lin, Yun Chen, Shu-Jen Yeh (2004-12): Traumatic Intramural Hematoma of the Duedenum: Report of One Case. Acta Paediatr Tw 45:343-45, 2004.


112. Yun Chen, Hong-Shiee Lai (2003-5,6): Non-operative treatment of idiopathic colonic perforation in a neonate. Formosan J Surg 36:147-150.


113. Chih-Hsien Wang, Swei-Ming Lin, Yun Chen, Sheng-Hong Tseng (2003-6): Multiple deep-seated carvernomas in the third ventricle, hypothalamus and thalamus: case report. Acta Neurochir (Wien) 45:505-508. (SCI)


114. Hong-Shiee Lai, Yun Chen, King-Jen Chang, Wei-Jao Chen (2003-6): Effects of octerotide on epidermal growth factor receptor, tissue plasminogen activator, and plasminogen activator inhibitor during intraperitoneal adhesion formation. J Gastroenterol 38:555-560. (SCI)


115. Chung-Shi Wen, Swei-Ming Lin, Yun Chen, Jin-Cherng Chen, Yao-Hung Wang, Sheng-Hong Tseng (2003-7): Radiation-induced temporary alopecia after embolization of a cerebral arteriovenous malformations: case report. Clin Neurol Neurosurg 105:215-7 (SCI).


116. Sheng-Hong Tseng, Chun-Chih Liao, Swei-Ming Lin, Yun Chen, Chia-Tung Shun (2003-7): Dural metastasis in patients with malignant neoplasm and chronic subdural hematoma. Acta Neurol Scand 108:43-46. (SCI)


117. Yun Chen, Sheng-Hong Tseng, Hong-Shiee Lai, Wei-Jao Chen (2003-12): Primary volvulus of the ileum in a preterm infant. J Formos Med Assoc 102:896-898. (SCI)


118. Sheng-Hong Tseng, Chun-Chih Liao, Swei-Ming Lin, Yun Chen, Chia-Tung Shun (2003-7): Dural metastasis in patients with malignant neoplasm and chronic subdural hematoma. Acta Neurol Scand 108:43-6. (SCI)


119. Yun Chen, Sheng-Hong Tseng, Hwang Lih-Hwa, Chiung-Nien Chen, King-Jen Chang (2002-11): Establishment and characterization of an orthotopic model of rectal cancer in mice: application to cytokine gene therapy. Int J Colorectal Dis 17:388-395. (SCI)


120. Yun Chen, Swei-Ming Lin, Hong-Shiee Lai, Sheng-Hong Tseng, Wei-Jao Chen (2002-9): Effects of irradiated tumor vaccine and continuous localized infusion of granulocyte-macrophage colony-stimulating factor on neuroblastoma in mice. J Pediatr Surg 37:1298-1304. (SCI)


121. Hong-Shiee Lai, Yun Chen, Wen-His Lin, Yen-Chun Liu, Wei-Lun Peng, Hsuan-I Lai (2002-9): The effects of cyclosporin A and FK506 on liver regeneration after partial hepatectomy in rats. Formosan J Surg 35:118-123.


122. Kuo-Chuan Wang, Swei-Ming Lin, Yun Chen, Sheng-Hong Tseng: Multiple tuberculous brain abscesses (2002-12): case report. Scan J Infect Dis 34:931-934. (SCI)


123. Chi-Yen Feng, Wen-Ming Hsu, Yun Chen (2001-2): Perforated peptic ulcer in an infant. J Formos Med Assoc 100(2):131-133. (SCI)


124. Yun Chen, Wen-Tsung Hung, Shih-Ming Chen, Sheng-Hong Tseng*(2002-4): Suppression of the elevated plasma interleukin-8 levels due to total ischemia and reperfusion of small intestine by luminal perfusion of fetal bovine serum. Pediatr Surg Int 18(4):107-9. (SCI)


125. Sheng-Hong Tseng, Yun Chen, Swei-Ming Lin, Chih-Hsien Wang (2002-2): Ruptured cervical disc after spinal manipulation therapy: report of two cases. Spine 27 E80-82. (SCI)


126. Sheng-Hong Tseng, Yun Chen, Swei-Ming Lin, Chih-Hsien Wang (2002-3): Cervical epidural hematoma after spinal manipulation therapy: case report. J Trauma 52:585-86. (SCI)


127. Yun Chen, Yen-Hsuan Ni, Chiu-Chiang Chen (2000): Neonatal intussusception due to cecal duplication cyst: case report. J Formos Med Assoc 99(4):352-3. (SCI)


128. Hong-Shiee Lai, Yun Chen, Wei-Jao Chen, King-Jen Chang, and LY Chiang (2000): Free radical scavenging activity of fullerenol on graft after small bowel transplantation in dogs. Transplant Proceed 32:1272-74.(SCI)


129. Hong-Shiee Lai, Yun Chen, Wen-Ming Hsu, King-Jen Chang, and Wei-Jao Chen (1999): Branched chain amino acid solution in total parenteral nutrition in pediatric surgical patients. Formosan J Surg 32(1):1-10.


130. Sheng-Hong Tseng, Yun Chen (1998): Occiput-cervical fusion for symptomatic atlantoaxial subluxation in a 32-month-old child with Down syndrome: a case report. Spinal Cord 36:520-22. (SCI)


131. Hong-Shiee Lai, Yun Chen, Wei-Jao Chen (1998): Carnitine contents in remnant liver, kidney, and skeletal muscle after partial hepatectomy in rats: randomized trial. World J Surg 22, 42-7. (SCI)


132. Hong-Shiee Lai, Yun Chen, King-Jen Chang, and Wei-Jao Chen (1998): Tissue plasminogen activator reduces intraperitoneal adhesion after intestinal resection in rats. J Formos Med Assoc 97(5):323-7. (SCI)


133. Sheng-Hong Tseng, Yun Chen, and C.T. Shun (1997): Isolated dural tuberculoma. Acta Neurochir(Wien) 139:263-4. (SCI)


134. Yun Chen, Hong-Shiee Lai, Wei-Jao Chen, Chiu-Chiang Chen, and Wen-Tsung Hung (1997): Gastroschisis—An eight-year experience. J Surg Assoc R.O.C 30(2): 92-7.


135. Hong-Shiee Lai, and Yun Chen (1996): Effect of Octreotide on postoperative intraperitoneal adhesions in rats. Scanc J Gastroenterol 31: 678-81.


136. Yun Chen, Hong-Shiee Lai, and Wei-Jao Chen (1996): Alterations of remnant liver carnitine and serum carnitine concentrations after partial hepatectomy in rats. Proceed NSC Part B: Life Sci. 20(1):14-8.


137. Hong-Shiee Lai, Shao-Yin Chu, Yun Chen, Chia-Hsuan Wu, and Lin-Tsu Lin (1994): Effect of pentoxifylline on intraperitoneal adhesions after intestinal resection in rats. J Formos Med Assoc 93:911-5.


138. Yun Chen, Hong-Shiee Lai, Yuan-Chao Duh, Jou-Kou Wang, and Ing-Sh Chiu (1996): Pentology of Cantrell corrected by one stage repair. J Formos Med Assoc 95(7):555-7.

研究計畫

計畫主持人

計畫名稱


執行年度
補助或委託機構

次世代定序技術(NGS)於小腸移植術後急性排斥診斷之應用(110-2314-B-418-001-MY3)


2021/08/01 ~2024/07/31

科技部

TREM-1引導巨噬細胞極化在小腸移植術後急性排斥反應之診斷及治療應用(108-2314-B-418-012)


2019/08/01 ~2021/07/31

科技部

RACK7對於神經母細胞瘤的腫瘤生成的作用(106-2314-B-418-007)


2017/08/01 ~2018/07/31

科技部

Neuroligin 3 與 neurexin 1β在神經母細胞瘤腫瘤發生所扮演的角色(105-2314-B-418-005)


2016/08/01 ~2017/07/31

科技部
核糖核苷酸還原酶抑制劑在神經母細胞瘤細胞的抑癌效果與機制探討(FEMH-2021-C-003)


2021/01/01 ~2021/12/31

亞東紀念醫院

CPEB1 在神經母細胞瘤的腫瘤抑制角色及機制探討(第二年)(FEMH-2020-C-003)


2020/01/01 ~2020/12/31

亞東紀念醫院

CPEB1 在神經母細胞瘤的腫瘤抑制角色及機制探討(FEMH-2019-C-003)


2019/01/01 ~2019/12/31

亞東紀念醫院

microRNAs 在 ZMYND8 對於神經母細胞瘤細胞的增殖分裂的作用的角色(FEMH-2018-C-003)


2018/01/01 ~2018/12/31

亞東紀念醫院
BS69 在神經母細胞瘤的腫瘤生成的角色(FEMH-2017-C-003)

2017/01/01 ~
亞東紀念醫院

得獎事蹟

2019 第七屆新北市醫療公益獎特殊貢獻個人獎 

2016 榮獲全國醫療典範獎 於第69屆醫師節慶祝大會副總統頒獎 

2013 小腸移植團隊獲生策會國家生技醫療品質獎銅獎 

2012 第一屆新北市醫療公益獎醫療貢獻個人獎 

2012 第十屆有庠傑出教授獎